Start at level 1 then slowly progress up to level 4 plus. Must be used alongside the Defence Creme or AVST moisturiser. Ingredients: Retinyl Propionate (A), Retinyl Palmitate (A), Vitamin C, Matrixyl 3000, Dermaxyl, Matrixyl Synthe 6, Juvinity & Malt Secrets. Directions: Apply 1-2 pumps of each product directly onto the face, neck and eye area AM & PM daily. Use C-quence Serum 4 Plus with the Defence Creme for 2 bottles before progressing to using the C-quence Serum 4 Plus with the Defence Creme Plus. These are very powerful skincare products that will make a difference to your skin. Boosting collagen to firm and tighten the skin. Boosts skin’s natural moisture. They need using correctly and slowly progressing up through the range with our guidance. Products to be used everyday AM & PM only, do not apply more than twice a day.