Supports: May support intestinal health. * Size: 2 oz liquid Suggested Usage: 10 to 30 drops 3 times per day or as directed by your healthcare professional. Contains: Proprietary Blend 1.5 mL Sienna (leaf), Cascara Sagrada (bark), Aloe Vera (leaf), Ginger (root), Barberry (root bark),Garlic (bulb), Cayenne (fruit) 35K HU, Filtered Water, Ethanol (20%). Liu L. W. (2011). Chronic constipation: current treatment options. Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 25 Suppl B(Suppl B), 22B–28B. Mueller-Lissner, S. A., & Wald, A. (2010). Constipation in adults. BMJ clinical evidence, 2010, 0413.