Visible Redness Reduction Calmwise Serum’s key ingredient, teprenone, has been found to visibly reduce skin redness in 1 month.* *Independent trial by Sederma Skin Barrier Support Helps to strengthen the skin’s barrier function against the redness-inducing effects of moisture loss and environmental stressors. Comfortable, Visibly Restored Skin The fragrance-free formula won’t aggravate irritated skin further but, instead, leaves it feeling calm, comfortable and visibly restored.