Cosmelan 2 Cream is a depigmenting topical cream that has an intensive corrective action on skin hyperpigmentation to inhibit and control the appearance of new dark spots It has a dual corrective and controlling action, achieving short- and long-term results by keeping hyperpigmentation under control. Cosmelan 2 is applied to clean, dry skin once per day at night. Apply Melan Recovery & Hydra Factor Vital K after it has absorbed into the skin. Always use Mesoprotech 130 to protect from UVA & UVB damage. We strongly recommend Cosmelan 2 cream be used in conjunction with the prescribed products from Mesoestetic