Advanced SenePlex+ Renewal Serum with Retinol supercharges your nighttime skincare regimen for quick, visible and sustained results. The powerful skin renewal serum targets the most frustrating signs of aging including wrinkles, sunspots, loss of firmness, and rough texture. You will see more radiance and visible results.Clinical Results Women love Advanced SenePlex Renewal Serum with Retinol! During a six-week independent consumer study, a majority of women agreed that their skin's overall appearance was improved, and their face appeared more youthful. Here's what else they said: 82% Improves skin clarity, leaving a healthy, even tone. 76% Reduces the appearance of crows feet around the eyes. 85% Improves skins overall appearance.73% Minimizes the appearance of fine lines and wrinkles. 88% Face appears more youthful. 85% Helps skin feel firmer.